Thayer's Greek Lexicon

 1. to corrupt, to destroy
  1) in the opinion of the Jews, the temple was corrupted or
"destroyed" when anyone defiled or in the slightest degree damaged
anything in it, or if its guardians neglected their duties
  2) to lead away a Christian church from that state of knowledge
and holiness in which it ought to abide
  3) to be destroyed, to perish
  4) in an ethical sense, to corrupt, deprave