The prohibition applies to the eating of flesh with blood in it, whether of living animals, as had been the barbarous custom of some pagan tribes in the past, or of slaughtered animals from which the blood had not been properly drained. This prohibition was, among other things, a safeguard against cruelty and a reminder of the sacrifice of animals, in which blood, as the bearer of life, was held sacred. God foresaw that man, easily falling victim to superstitious beliefs, would think that, in partaking of the life-bearing fluid of animals, his own life power would be either strengthened or prolonged. For these and probably other reasons not now clear to us, the eating of flesh with the blood in it was irrevocably prohibited. The apostles considered this prohibition still binding in the Christian Era. They especially drew the attention of Gentile Christian believers to it, because these new believers, before their conversion, had been accustomed to the eating of flesh with blood in it (Acts 15:20, 29).
“Life,”nephesh (see on Gen. 2:7). To translate it “soul,” as some have done, obscures the true meaning (see Lev. 17:11). Blood is vital to life. If the circulation of blood to any part of the body is cut off, that part dies. A complete loss of blood inevitably brings death. This being true, the Hebrew word nephesh, standing parallel to “blood” in this text, should be rendered “life,” as in the KJV.